In a groundbreaking study, researchers have successfully produced offspring from mice with two fathers and no mother—a first ...

Mice with two fathers and no mother have now had offspring of their own. The study is a breakthrough in androgenesis – that ...

Researchers at Shanghai Jiao Tong University have produced fertile adult mice from embryos constructed entirely with male ...

The pregnant ICR mouse and JAR cell (a monolayer model), in combination with molecular docking, were used to explore the underlying mechanism. OPFRs were rapidly metabolized into diester metabolites ...

This ICR mouse colony was categorized as monitored animal and maintained in Low Barrier System with Heating, Ventilating, and Air Conditioning (HVAC) system. Their microbiological status was ...

Animal studies also showed promising results. In mice with resistant prostate cancers, NXP800 significantly slowed tumour growth. Without the drug, all tumours had doubled in size by 38 days; with ...

A novel real-time motion analysis system was developed for detecting the scratching behavior of laboratory mice in long-time experiments, which enables automated behavior quantification for new drug ...

Objective: Ileocaecal resection (ICR) is common in Crohn’s disease. Inflammation and fibrosis frequently recur at the site of anastomosis or in the small intestine (SI). No animal models of ...

Pregnant ICR mice were purchased from Japan SLC and used for in utero electroporation and microarray analyses. Lpar1-EGFP mice (Tg (Lpar1-EGFP)GX193Gsat) were obtained from MMRRC.

Initially, the HPC model was established by hypoxia stimulations on ICR mice. We found that HPC downregulated the expression of DNA methyltransferase (DNMT) 3A and DNMT3B. Then, the upregulation of ...

The electrocardiogram (ECG) is an effective tool for monitoring various health conditions, and animal studies using ECG have uncovered new information about complex diseases. However, monitoring ...