Oman and Qatar were leading efforts to begin ceasefire talks, while mediators said Iran was open to resuming nuclear negotiations if Israel’s attacks stop.

By Alexander Cornwell and Parisa Hafezi TEL AVIV/DUBAI (Reuters) -Israel and Iran attacked each other for a fifth straight day on Tuesday, and U.S. President Donald Trump urged Iranians to evacuate Tehran,

Iranian officials have warned that U.S. participation in an attack on its facilities will imperil any chance of the nuclear disarmament deal the president insists he is still interested in pursuing.

The White House and Israeli Ministry of Foreign Affairs did not immediately respond to The Post’s request for comment.

Israel has struck major nuclear and military sites and killed leading commanders and nuclear scientists in Iran, which has responded with its own volley of drones and missiles on Israel.

After a new wave of Israeli strikes on Iran's capital -- including a dramatic attack on a state TV building -- both countries activated their missile defence systems overnight.

Iran fired a new wave of missile attacks on Israel early Monday, triggering air raid sirens across the country as emergency services reported at least five killed and dozens more wounded in the fourth day of a conflict between the regional foes that showed no sign of slowing.

"American Forces are maintaining their defensive posture & that has not changed," the chief Pentagon spokesperson said.