There are other reasons researchers were surprised that unusual ribosomes lay behind the unusual development of these mutant mice. First, quality control on ribosomes is tight: Since faulty ones ...

Summarizing these findings, White noted that: “We found that the development of epithelial cell populations in the thymus critical for negative T cell selection was impaired in mutant mice.

Further testing showed this method killed mutant HER2 cancer cells in dishes but spared normal ones. When the researchers tested their T-cell engagers in mice with mutant HER2 tumors, the ...

Engineered polymers interfere with protein interactions to protect cell health in a mouse study. Researchers at Northwestern University and Case Western Reserve University have developed the first ...

Researchers developed a polymer that delivers peptides to prevent toxic protein aggregation in Huntington’s disease. The ...

They discovered that drugs known as carbonic anhydrase inhibitors—of which the glaucoma drug methazolamide is one—clear tau ...

Further testing showed this method killed mutant HER2 cancer cells in dishes but spared normal ones. When the researchers tested their T-cell engagers in mice with mutant HER2 tumors, the ...

Breakthrough polymer-based therapy shows promise in reversing Huntington's disease symptoms by preventing toxic protein ...

Glaucoma drug methazolamide shows potential in fighting neurodegenerative diseases, offering new hope for treating conditions ...

The manuscript “Amphiphile-engineered DNA adjuvants stimulate strong type I IFN production in lymph nodes via cytosolic danger-sensing to induce potent cellular and humoral immunity in mice and ...

Studies support the idea of “polymers as therapeutics,” rather than polymers as carriers of drug molecules in the sense of ...