Recurrent respiratory papillomatosis (RRP) is a rare complication of human papillomavirus infection, resulting in exophytic growths into the respiratory tract. A primigravida patient with RRP ...

Hereditary angioedema (HAE) is a genetic disorder that causes sudden episodes of swelling, often accompanied by abdominal pain. Affecting roughly 1 in 50 000 people, HAE typically appears in childhood ...

A woman in her 40s with a history of a subarachnoid haemorrhage complicated by ischaemic infarcts presented with 1 week of ...

Perianal Paget’s disease (PPD) is a rare condition which is often associated with underlying malignancy. To definitively rule ...

Neurofibromatosis Type 1 (NF1) is a genetic disorder characterised by benign tumours and cutaneous lesions, including neurofibromas. This case report describes a boy in his early 10s with NF1 who ...

Patients with inoperable hepatobiliary cancers often endure severe abdominal pain, which impacts their quality of life. This pain is usually a combination of both nociceptive and neuropathic pain, ...

Leptomeningeal disease is rare in pancreatic cancer and prognosis remains poor. Mutation profiles are now directing therapy to improve survival. We describe a case of leptomeningeal and brain ...

Hydroxyl-methyl-glutaryl-Co-A reductase (HMGCR) immune mediated necrotising myopathy (IMNM) is a rare autoimmune myositis that is thought to be triggered by statins and responds to immunomodulation.

Primary adenocarcinoma of the female urethra is a rare entity. Its incidence increases with age with the highest rate in women aged more than 65 years. Adenocarcinoma of the urethra is more common ...

Portopulmonary hypertension (PoPH) is a poorly understood complication of liver disease which affects about 10% of patients with pulmonary hypertension. This case report outlines the difficulties in ...

By definition, anteroposterior (AP) compression type 1 (APC-1) injury is a type of pelvic ring injury, which is widely acknowledged as ‘stable’. Unstable forms of this injury are very rare and present ...

Acquired haemophilia A is a rare condition defined by the presence of coagulation inhibitors, which are autoantibodies directed against factor VIII that interfere with its activity. We report a case ...