Iran and the United States will hold talks Friday in Rome, their fifth round of negotiations over Tehran’s rapidly advancing nuclear program.

Depending on who you ask, a nuclear agreement between Iran and the United states is either a non-starter or almost a done deal.

Iran and the United States are set to resume nuclear talks in Rome amid rising tensions, hard-line demands, and Israeli threats of military action. With uranium enrichment at the core of the standoff,

Iran’s top diplomat has warned that his country would take “special measures” to defend its nuclear facilities if Israel continues to threaten them, raising the stakes further ahead of a new round of talks with the United States.