A combined Russian missile and drone attack on Ukraine overnight killed at least 15 people — including an American citizen — and wounded scores of others, according to Ukrainian officials.

Russia's overnight drone assault targeted the southern Ukraine port city of Odesa and the northeastern city of Kharkiv, hitting apartment blocks, officials said. The barrage of more than 20 drones injured almost two dozen civilians, including girls aged 12 and 17, Ukrainian President Volodymyr Zelenskyy said.

Russia launched 315 drones at Ukraine overnight into Tuesday, in what Ukrainian President Volodymyr Zelensky said was “one of the largest” attacks on the capital Kyiv, with local officials in the southern port city of Odesa also reporting a maternity ward there had been hit.